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Antibiotics – what is it?

Antibiotics are substances of biological origin, synthesized by microorganisms, which tend to both inhibit the growth of pathogenic organisms and completely destroy them.

Just some 100 years ago, people died from ailments such as meningitis, pneumonia, and many other infectious diseases. Their death was due to the absence of any antimicrobial agents. It turns out that antibiotics saved people from extinction. It was with their help that it was possible to reduce the mortality of patients with various infectious diseases by hundreds, and sometimes thousands of times.

What are the antibiotics?

To date, more than 200 antimicrobials have been created, of which more than 150 are used to treat children. Their sophisticated names often baffle people who are not related to medicine. How to understand the abundance of intricate terms? All antibiotics are divided into groups – depending on the method of exposure to microorganisms. The first group is bactericidal antibiotics, they act on microbes, destroying them. The second group is bacteriostats, they inhibit the growth of bacteria.

Penicillins

These are substances of natural origin, formed from various types of green mold (Penicillium mushroom). All are intended for parenteral administration. The different duration of action is explained by unequal solubility in water. They are rapidly absorbed into the blood, their maximum amount in the blood during administration is noted after 30-60 minutes, and excreted after 3-4 hours, so the intervals between injections should not be more than 4-6 hours.

Cephalosporins

They were isolated from the culture of Cefalosporinum fungi found in the seawater of Sardinia, near the place of sewage discharge. The mechanism of action is associated with impaired synthesis of the bacterial cell wall and is fundamentally no different from the mechanism of action of penicillins and broad-spectrum antibiotics. Cefazolin is used for soft tissue infections and perioperative prophylaxis for surgical interventions.

Macrolides

They are vital products of radiant mushrooms. They are fairly safe drugs. Adverse reactions, like diarrhea, allergic reactions, damage of the liver, rarely occur. An example is erythromycin – the first and one of the safest antibiotics, in terms of the development of severe adverse reactions.

Tetracyclines

Doxycycline is the best tetracycline group antibiotic to date and is virtually food independent. High levels are achieved with treatment in bronchial secretions, sinuses, bile, and prostate gland.

How long should be antibiotics taken?

In most acute diseases, it is given within 2-3 days after the temperature drops, but there are exceptions. So, otitis media is usually treated with amoxicillin for no more than 7-10 days, and tonsillitis – for at least 10 days, otherwise there may be a relapse.

Are antibiotics and dysbiosis always together?

Since antibiotics suppress the normal flora of the body, they can cause dysbiosis, i.e., reproduction of pathogenic bacteria or fungi that are not characteristic of the intestine. However, only in rare cases, such dysbiosis is dangerous: with short courses of antibiotic treatment, manifestations of dysbiosis are extremely rare. So antifungal and lactobacterium drugs are used to prevent dysbiosis only in cases of prolonged treatment with several drugs with a wide antibacterial spectrum.

What side effects are possible with antibiotics?

The dangers associated with taking antibiotics are often exaggerated, but they must always be remembered. We have already talked about dysbiosis. Another danger lurking when taking antibiotics is an allergy. Some people (including infants) are allergic to penicillins and other antibiotic drugs: rashes, shock reactions (the latter, fortunately, are very rare). If a reaction to a particular antibiotic has already been observed, you should definitely inform your doctor about it, and he will easily pick up a replacement. Allergic reactions are especially frequent in cases where an antibiotic is given to a patient suffering from a disease of a non-bacterial (viral) nature: the fact is that many bacterial infections seem to reduce the patient’s “allergic readiness,” which reduces the risk of a reaction to the antibiotic.

The most severe adverse events are specific lesions of organs and systems that develop under the influence of individual drugs. That is why only drugs that have been well studied for many years are those that are approved for use in children of younger age groups (and pregnant women).

Antibiotics are the achievement of civilization that we should not refuse, but we must use them correctly, only under the supervision of a doctor, and strictly according to indications!